We study computational and experimental RNA biology.

RNA regulation linking genetics and disease

The epitranscriptome and its regulation

Recent Publications

2024

Fu, Ting; Amoah, Kofi; Chan, Tracey W.; Bahn, Jae Hoon; Lee, Jae-Hyung; Terrazas, Sari; Chong, Rockie; Kosuri, Sriram; Xiao, Xinshu

Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes Journal Article

In: Nature Communications, vol. 15, no. 3335, 2024.

Links | BibTeX

Huang, Elaine; Frydman, Clara; Xiao, Xinshu

Navigating the landscape of epitranscriptomics and host immunity Journal Article

In: Genome Res, vol. 34, no. 4, pp. 515–529, 2024, ISSN: 1549-5469.

Abstract | Links | BibTeX

Zheng, Rong; Dunlap, Mikayla; Bobkov, Georg O M; Gonzalez-Figueroa, Carlos; Patel, Khushali J; Lyu, Jingyi; Harvey, Samuel E; Chan, Tracey W; Quinones-Valdez, Giovanni; Choudhury, Mudra; Roux, Charlotte A Le; Bartels, Mason D; Vuong, Amy; Flynn, Ryan A; Chang, Howard Y; Nostrand, Eric L Van; Xiao, Xinshu; Cheng, Chonghui

hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing Journal Article

In: Mol Cell, 2024, ISSN: 1097-4164.

Abstract | Links | BibTeX

Quinones-Valdez, Giovanni; Amoah, Kofi; Xiao, Xinshu

Long-read RNA-seq demarcatescis- andtrans-directed alternative RNA splicing Unpublished

bioRxiv, 2024.

Abstract | Links | BibTeX

Hervoso, Jonatan L; Amoah, Kofi; Dodson, Jack; Choudhury, Mudra; Bhattacharya, Arjun; Quinones-Valdez, Giovanni; Pasaniuc, Bogdan; Xiao, Xinshu

Splicing-specific transcriptome-wide association uncovers genetic mechanisms for schizophrenia Journal Article

In: Am J Hum Genet, 2024, ISSN: 1537-6605.

Abstract | Links | BibTeX

Recent News

November 27, 2024

Check out the paper and the cover image by the Villanueva lab at Cell Reports.  Siqi and I are glad to have contributed to this paper.

November 9, 2024
Congratulations to Gio for winning one of the 3 postdoctoral Research Excellence Award at ASHG!
November 8, 2024

Elaine presented a fantastic platform talk at the 2024 ASHG Annual meeting.

November 7, 2024

Jonatan’s poster presentation on SpliTWAS was a hit at ASHG!

November 5, 2024

Gio gave a fantastic plenary presentation at the 2024 ASHG Annual meeting!