We study computational and experimental RNA biology.

RNA regulation linking genetics and disease

The epitranscriptome and its regulation

Recent Publications

2023

Chan, Tracey W; Dodson, Jack P; Arbet, Jaron; Boutros, Paul C; Xiao, Xinshu

Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis Journal Article

In: Cancer Res, vol. 83, no. 3, pp. 374–385, 2023, ISSN: 1538-7445.

Abstract | Links | BibTeX

R, Zheng; M, Dunlap; J, Lyu; C, Gonzalez-Figueroa; G, Bobkov; SE, Harvey; TW, Chan; G, Quinones-Valdez; M, Choudhury; A, Vuong; RA, Flynn; HY, Chang; X, Xiao; C, Cheng

LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity Online

2023, visited: 24.02.2023.

Links | BibTeX

2022

Lefaudeux, Diane; Sen, Supriya; Jiang, Kevin; and, Alexander Hoffmann

Kinetics of mRNA nuclear export regulate innate immune response gene expression Journal Article

In: Nat Commun, vol. 13, no. 1, pp. 7197, 2022, ISSN: 2041-1723.

Abstract | Links | BibTeX

He, Jingyan; Fu, Ting; Zhang, Ling; Gao, Lucy Wanrong; Rensel, Michelle; Remage-Healey, Luke; White, Stephanie A; Gedman, Gregory; Whitelegge, Julian; Xiao, Xinshu; Schlinger, Barney A

Improved zebra finch brain transcriptome identifies novel proteins with sex differences Journal Article

In: Gene, vol. 843, pp. 146803, 2022, ISSN: 1879-0038.

Abstract | Links | BibTeX

Quinones-Valdez, Giovanni; Fu, Ting; Chan, Tracey W; Xiao, Xinshu

scAllele: A versatile tool for the detection and analysis of variants in scRNA-seq Journal Article

In: Sci Adv, vol. 8, no. 35, pp. eabn6398, 2022, ISSN: 2375-2548.

Abstract | Links | BibTeX

Recent News

February 24, 2023

Our collaborative paper with Dr. Chonghui Cheng’s lab is now on BioRxiv: “LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity” Congratulations to Carlos, Tracy, Giovanni, Mudra and everyone in the Cheng lab!

January 3, 2023

Congratulations to Elaine for successfully advancing to PhD candidacy!

January 1, 2023

Congratulations to Carlos for receiving a diversity grant from NIH!

December 3, 2022

Carlos gave a fantastic presentation at at UCLA’s riboforum!