We study computational and experimental RNA biology.

RNA regulation linking genetics and disease

The epitranscriptome and its regulation

Recent Publications


Chan, Tracey W; Dodson, Jack P; Arbet, Jaron; Boutros, Paul C; Xiao, Xinshu

Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis Journal Article

In: Cancer Res, vol. 83, no. 3, pp. 374–385, 2023, ISSN: 1538-7445.

Abstract | Links | BibTeX

R, Zheng; M, Dunlap; J, Lyu; C, Gonzalez-Figueroa; G, Bobkov; SE, Harvey; TW, Chan; G, Quinones-Valdez; M, Choudhury; A, Vuong; RA, Flynn; HY, Chang; X, Xiao; C, Cheng

LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity Online

2023, visited: 24.02.2023.

Links | BibTeX

Choudhury, Mudra; Fu, Ting; Amoah, Kofi; Jun, Hyun-Ik; Chan, Tracey W; Park, Sungwoo; Walker, David W; Bahn, Jae Hoon; Xiao, Xinshu

Widespread RNA hypoediting in schizophrenia and its relevance to mitochondrial function Journal Article

In: Sci Adv, vol. 9, no. 14, pp. eade9997, 2023, ISSN: 2375-2548.

Abstract | Links | BibTeX

Khan, Arshad H; Bagley, Jared R; LaPierre, Nathan; Gonzalez-Figueroa, Carlos; Spencer, Tadeo C; Choudhury, Mudra; Xiao, Xinshu; Eskin, Eleazar; Jentsch, James D; Smith, Desmond J

Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice Journal Article

In: Cell Rep, vol. 42, no. 8, pp. 112856, 2023, ISSN: 2211-1247.

Abstract | Links | BibTeX

Liu, Zhiheng; Quinones-Valdez, Giovanni; Fu, Ting; Huang, Elaine; Choudhury, Mudra; Reese, Fairlie; Mortazavi, Ali; Xiao, Xinshu

L-GIREMI uncovers RNA editing sites in long-read RNA-seq Journal Article

In: Genome Biol, vol. 24, no. 1, pp. 171, 2023, ISSN: 1474-760X.

Abstract | Links | BibTeX

Recent News

October 23, 2023

Our paper on “dsRID: in silico identification of dsRNA regions using long-read RNA-seq data” is published at Bioinformatics. Congratulations to Ryo, Zhiheng and Mudra!

October 5, 2023

Congratulations to Giovanni and Kofi for winning the Poster Award at the QCB retreat!

October 2, 2023

We welcome Raj Varada to our lab!

October 1, 2023

We welcome Jiaxi Liu to our lab!

September 26, 2023

Our Lab presented our research at the QCB retreat (Gio: platform presentation; Gio/Kofi, Jack, Jonatan, Ryo with poster presentations)!